ABSTRACT
In the published article, the title was published incorrectly as COVID-19.
ABSTRACT
Viral infections are frequent among patients with thoracic malignancies prompted by dysregulation of innate and adaptative immune response. Clinical symptoms and radiological findings of both viral pneumonia and lung adenocarcinoma may overlap resulting in diagnostic and clinical challenges.We present the case of a women admitted to our department presenting with an acute manifestation of coronavirus OC43 pneumonia with underlying undiagnosed lung adenocarcinoma.
Subject(s)
Adenocarcinoma of Lung/diagnosis , Betacoronavirus , Coronavirus Infections/diagnosis , Incidental Findings , Lung Neoplasms/diagnosis , Pneumonia, Viral/diagnosis , Adenocarcinoma of Lung/complications , Adult , COVID-19 , Coronavirus Infections/complications , Female , Humans , Lung Neoplasms/complications , Pandemics , Pneumonia, Viral/complications , SARS-CoV-2 , Tomography, X-Ray ComputedABSTRACT
The elderly may represent a specific cluster of high-risk patients for developing COVID-19 with rapidly progressive clinical deterioration. Indeed, in older individuals, immunosenescence and comorbid disorders are more likely to promote viral-induced cytokine storm resulting in life-threatening respiratory failure and multisystemic involvement. Early diagnosis and individualized therapeutic management should be developed for elderly subjects based on personal medical history and polypharmacotherapy. Our review examines the pathogenesis and clinical implications of ageing in COVID-19 patients; finally, we discuss the evidence and controversies in the management in the long-stay residential care homes and aspects of end-of-life care for elderly patients with COVID-19.